Successful treatment of antiepileptic drug hypersensitivity syndrome with intravenous immune globulin.
نویسندگان
چکیده
Intravenous immune globulin (IVIG) has proved beneficial for severe immunologically related cutaneous adverse reactions. We report a child with severe antiepileptic drug hypersensitivity syndrome who was successfully treated with IVIG. IVIG should be considered in the pharmacologic armamentarium of severe antiepileptic drug hypersensitivity syndrome. antiepileptic drugs, hypersensitivity, immune globulin.
منابع مشابه
Experience with intravenous immunoglobulin in severe childhood atopic dermatitis.
6. Shiohara T, Inaoka M, Kano Y. Drug-induced hypersensitivity syndrome (DIHS): a reaction induced by a complex interplay among herpesviruses and antiviral and antidrug immune responses. Allergol Int. 2006;55:1--8. 7. Picard D, Janela B, Descamps V, D’Incan M, Courville P, Jacquot S, et al. Drug reaction with eosinophilia and systemic symptoms (DRESS): a multiorgan antiviral T cell response. Sc...
متن کاملAnticonvulsant hypersensitivity syndrome: report of 2 cases from Kuwait.
OBJECTIVE To illustrate the clinical features, laboratory findings, and management of anticonvulsant hypersensitivity syndrome (AHS), emphasizing the importance of recognizing its multiple clinical components and raising awareness of the cross-sensitivity among different anticonvulsants. CLINICAL PRESENTATION AND INTERVENTION Two cases of AHS due to carbamazepine and a combination of sodium v...
متن کاملLamotrigine-induced Hypersensitivity Syndrome: Case Report
Anticonvulsant hypersensitivity syndrome (AHS) is a life-threatening, idiosyncratic, non-dose related adverse reaction reported to occur with aromatic antiepileptic drugs. We present an 11-year-old girl diagnosed with hypersensitivity syndrome with a fever, rash, lymphadenopathy, and hepatic and pulmonary involvement. Although timely recognition of the signs and symptoms, discontinuation of the...
متن کاملClinical Features and Treatment Outcomes of 132 Infants with Immune Thrombocytopenic Purpura
Introduction: To determine common clinical symptoms, admission length, and treatment outcomes of infants with Immune Thrombocytopenic Purpura. Method: analysis of 132 infants with Immune Thrombocytopenic Purpura admitted to the emergency and hematology ward of Dr. Sheikh Hospital, with reference to age, gender, immunization history (preceding six weeks), presenting clinical features, treatment...
متن کاملImmunotoxic Effects of Lambda-cyhalothrin in Rabbits
The effect of Lambda-cyhalothrin on the immune response was studied in rabbits exposed to the insecticide via food at concentrations of 1373.23, 686.76 or 343.38 ppm (equivalent to 1/10, 1/20 and 1/40 oral LD50, respectively) for 8 weeks. The humoral immune response was measured by determination of the antibody titre against sheep red blood cells (SRBC), a T cell dependent antigen. Moreover, th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Pediatrics
دوره 107 1 شماره
صفحات -
تاریخ انتشار 2001